Headlined by a Sept. 9 Super Bowl rematch between the Seahawks and Patriots, as well as the NFL’s first-ever game in Australia between the Rams and 49ers, Week 1 is absolutely loaded. Here are the lines for every Week 1 matchup at bet365 Sportsbook as of Sept. 11. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports. Patriots 10, Seahawks 13 Spread: Seahawks -3.5 (NE covers)O/U: 44.5 (Under hits) 49ers 27, Rams 7 Spread: Rams -3.5 (SF covers)O/U: 48.5 (Under hits) Falcons @ Steelers Spread: Steelers -5.5Moneyline: Steelers -245, Falcons +200O/U: 41.5 Ravens @ Colts Spread: Ravens -3.5Moneyline: Ravens -180, Colts +150O/U: 47.5 Bills @ Texans Spread: Bills -1.5Moneyline: Bills -120, Texans +100O/U: 44.5 Bears @ Panthers Spread: Bears -3.5Moneyline: Bears -170, Panthers +145O/U: 47.5 Browns @ Jaguars Spread: Jaguars -8.5Moneyline: Jaguars -425, Browns +325O/U: 40.5 Saints @ Lions Spread: Lions -6.5Moneyline: Lions -330, Saints +265O/U: 49.5 Jets @ Titans Spread: Titans -1.5Moneyline: Titans -120, Jets +100O/U: 38.5 Buccaneers @ Bengals Spread: Bengals -3.5Moneyline: Bengals -200, Buccaneers +165O/U: 50.5 Cardinals @ Chargers Spread: Chargers -9.5Moneyline: Chargers -500, Cardinals +375O/U: 47.5 Packers @ Vikings Spread: Vikings -1.5Moneyline: Vikings -125, Packers +105O/U: 46.5 Dolphins @ Raiders Spread: Raiders -3.5Moneyline: Raiders -170, Dolphins +145O/U: 40.5 Commanders @ Eagles Spread: Eagles -5.5Moneyline: Eagles -240, Commanders +195O/U: 44.5 Cowboys @ Giants Spread: Cowboys -2.5Moneyline: Cowboys -160, Giants +135O/U: 48.5 Broncos @ Chiefs Spread: Chiefs -2.5Moneyline: Chiefs -150, Broncos +125O/U: 43.5